Lack of muscle strength affects the development of ALS

Lack of muscle strength affects the development of ALS

Low muscle strength in the late adolescence is a risk factor for the development of neurodegenerative diseases. To this conclusion came the research team from the Academy of Salgren and the University of Gothenburg. The results of the work of specialists were published today on the website of the Gothenburg University.

Lack of muscle tone can lead to a number of diseases: A sedentary lifestyle and muscle weakness cause obesity and cardiovascular diseases, which is why doctors recommend at least half an hour a day to be physically stressed from the youngest age. However, a new study showed that lack of physical fitness can be a risk factor for diseases that were previously considered congenital.

In their work, researchers studied the military draft of more than 1.8 million young men in the period from 1968 to 2005. The obtained data were compared with the data of the Swedish health register. At the time of the appeal, most teenagers turned 18 years old. Scientists have observed their state of health for almost 46 years. In the course of observations, a group of 526 people was identified, who eventually developed amyotrophic lateral sclerosis (ALS), a fatal disease in which the nerves controlling the muscles degrade.

A detailed analysis showed that men with ALS differed from other recruits only in three parameters: BMI, the number of red blood cells and the strength of muscles. At the same time, if the gap in the values ​​of BMI was practically insignificant (in the group with ALS 21.1, in healthy people 21.9), the level of oxygen-containing red blood cells in patients with multiple sclerosis was much lower, like the total muscle strength in the hands and feet. Thus, the lack of muscle tone increased the risk of ALS in 30 years. However, scientists can not yet explain the nature of this relationship, especially without data that would also affect women.


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